The PM on Thursday could face his first setback, when voters in the Brecon and Radnorshire constituency, in South Wales, votie in a by-election.
The sitting Tory MP, Chris Davies, was convicted of filing false expenses and 18,000 voters signed a petition to recall him.
Conservatives then shocked many by selecting Mr Davies to stand again, although there may be method in the madness – the party believes they can portray the recall petition as a politicised overreaction to an honest mistake.
The Liberal Democrats are heavy favourites to win the election, having made a pact with the Greens and Plaid Cymru to ensure theirs is the only pro-Remain candidate.
The Lib Dems have put forward Jane Dodds, their leader in Wales, as their candidate and are chucking huge resources at the campaign.